A History of Epidemiologic Methods and Concepts by Alfredo Morabia (auth.), Alfredo Morabia (eds.)

By Alfredo Morabia (auth.), Alfredo Morabia (eds.)

Methods, simply as illnesses or scientists, have their very own background. it is crucial for scientists to concentrate on the genesis of the tools they use and of the context during which they have been developed.

A heritage of Epidemiologic tools and Concepts is predicated on a set of contributions which seemed in "SPM overseas magazine of Public Health", beginning in January 2001. The contributions specialise in the old emergence of present epidemiological equipment and their relative value at varied deadlines, instead of on particular achievements of epidemiology in controlling plagues akin to cholera, tuberculosis, malaria, typhoid fever, or lung melanoma. The papers current the layout of potential and retrospective reports, and the strategies of bias, confounding, and interplay. The compilation of articles is complemented by way of an creation and reviews via Prof. Alfredo Morabia which places them within the context of present epidemiological research.

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In this book, Louis reports the following experiment. He had a large collection of case descriptions, which he had accrued during years of intensive clinical activity and autopsy in the Parisian Hospital La Charite. He found in his clinical records a total of 77 patients who were comparable because they had a well-characterized form of pneumonia (Morabia and Rochat, 2001) and were in perfect health at the time of the first symptoms of the disease. Twenty-seven of them had died. For each patient he computed the duration of illness from disease onset to death or recovery.

Deaths are in the numerator and sick people are in the denominator. , 100) sick". Farr also refers to it as the "mean rate of dying per unit of sick time". To compute the force of mortality, Farr divides the number of deaths by the product of the number of persons sick and the average duration during which they were sick. If 2,142 cases of cholera have been sick an average of 7 days each, this corresponds to a total of [7 x 2,142 =] 14,994 days of sickness, or sick person-days. Sick-person days divided by 365 days in a year gives 41 years of sickness or 41 sick person-years.

The relation of prevalence to incidence is quite straightforward: " ... , 1960, p. 61 ). Prevalence may increase because patients survive longer with their disease. , years). Table 7 shows that both acute and chronic leukemia have similar incidence rates (about 30 per million per year), but that chronic leukemia is eight times more prevalent than acute leukemia. 4 months for acute leukemia and 20 months for chronic leukemia derived from independent follow-up of these same patients. The conceptual link between prevalence, incidence rate and duration is perfectly illustrated in this example.

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