Amylin: Physiology and Pharmacology by Andrew Young

By Andrew Young

Deciphers amylin's body structure and divulges formerly unrecognized mechanisms basic to manage bodyweight and gasoline homeostasis. additionally discusses healing application of amylin because the first new medication to regard diabetes considering insulin.

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Pancreatic beta cell expression of amylin in streptozotocin‐induced diabetes in rats. Diabetes 39, 143A. , Ghatei, M. , and Bloom, S. R. (1990). Islet amyloid polypeptide‐like immunoreactivity (amylin) in rats treated with dexamethasone and streptozotocin. J. Endocrinol. 126, 425–429. , Wang, Z. , Ghatei, M. , and Bloom, S. R. (1991). Changes in islet peptide content after dexamethasone treatment. J. Endocrinol. 129, 93. , Ghatei, M. , and Bloom, S. R. (1993). Molecular form of islet amyloid polypeptide (amylin) released from isolated rat islets of Langerhans.

Clin. Sci. (Colch) 81, 803–808. Gill, A. , and Yen, T. T. (1991). Effects of ciglitazone on endogenous plasma islet amyloid polypeptide and insulin sensitivity in obese‐diabetic viable yellow mice. Life Sci. 48, 703–710. , and Mertz, R. (1991). Co‐ordinate regulation of insulin and amylin secretion from rat islets of Langerhans and HIT‐T15 b‐cells. J. Cell Biochem. 15B, 66. , and Nanjo, K. (1992). Islet amyloid polypeptide (IAPP) secretion from islet cells and its plasma concentration in patients with non‐insulin‐dependent diabetes mellitus.

1994). Islet amyloid polypeptide is expressed in endocrine cells of the gastric mucosa in the rat and mouse. Gastroenterology 107, 712–719. , and Sundler, F. (1995a). Non‐parallelism of islet amyloid polypeptide (amylin) and insulin gene expression in rat islets following dexamethasone treatment. Diabetologia 38, 395–402. , and Sundler, F. (1995b). Differential expression of islet amyloid polypeptide (amylin) and insulin in experimental diabetes in rodents. Mol. Cell Endocrinol. 114, 101–109. , and Sundler, F.

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