Basic and Clinical Endocrinology by Francis S. Greenspan, David G. Gardner

By Francis S. Greenspan, David G. Gardner

The best-selling reference in endocrinology! Authoritative, concise, and present, this "all-in-one" textual content specializes in the pathophysiology, analysis, and therapy of endocrine issues. Written by means of famous experts and that includes greater than 350 two-color illustrations, the 7th variation has been up-to-date to mirror the most recent in diagnostic trying out and molecular biology in addition to new methods to clinical administration.

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D. Bikle, E. Gee, Free, and not total, 1,25-dihydroxyvitamin D regulates 25-hydroxyvitamin D metabolism by keratinocytes, Endocrinology 124 (2) (1989) 649–654. [42] A. Nykjaer, D. Dragun, D. Walther, H. Vorum, C. Jacobsen, J. , An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3, Cell 96 (4) (1999) 507–515. L. Lauridsen, P. Vestergaard, E. Nexo, Mean serum concentration of vitamin D-binding protein (Gc globulin) is related to the Gc phenotype in women, Clin.

Scand. 47 (1959) 160–168. [2] M. Speeckaert, G. R. E. Taes, Biological and clinical aspects of the vitamin D binding protein (Gc-globulin) and its polymorphism, Clin. Chim. Acta 372 (1–2) (2006) 33–42. E. G. Haddad, Vitamin D binding protein (Gc-globulin), Endocr. Rev. 10 (3) (1989) 294–307. H. K. A. E. Cooke, Physical and meiotic mapping of the region of human chromosome 4q11–q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster, Genome Res. 9 (6) (1999) 581–587.

The reduction could be caused by the replacement of functional liver parenchyma by connective tissue. However, also a secondary response could explain those findings due to changes in lipid and vitamin metabolism, as the clinical course of liver fibrosis is associated with increased cholestasis and decreased small intestinal bile acid concentrations. This leads to an impaired absorption of lipids and fat-soluble vitamins [157]. 7. 1 Asthma Little is known about the role of DBP in children with asthma.

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